Integrative Biology and Physiology Phenotyping Cores
Using the Core
How do I request a procedure?
Request room reservations by contacting the Core Manager:
Pilar Ariza-Guzman, DVM, MS
To discuss specific experiments you would like to perform using the IBP Phenotyping Core services please contact the Core Director at firstname.lastname@example.org.
The Phenotyping Cores in Jackson Hall and in the Cardiovascular and Cancer Research Building (CCRB) are designed to serve the bio-sciences to integrate disciplines by offering the opportunity for investigators to use highly specialized equipment to conduct their research and have access to highly skilled services and surgeries.
The Cores will be able to give affordable service for any internal or external researchers who may need it.
Phenotyping Core services
The Integrative Biology and Physiology (IBP) Phenotyping Core facility is now offering a wide range of mice cardio-metabolic physiology services in our state-of-the-art CCRB and Jackson Hall (JH) facilities (JH only for surgery and telemetry).
The services offered by the IBP Phenotyping Core include:
- Body composition analysis: Echo-MRI 3-in-1 (Echo Medical Systems LLC, Houston, TX);
- Whole animal energy expenditure (Oxymax/CLAMS Lab Animal Monitoring System (Columbus Instruments, Columbus, OH): equipped with O2/CO2 sensors and X,Z activity monitors. The system is completed by environmental enclosures for precise light/temperature (4 to 30C range) control;
- Automated Food Consumption and meal pattern analysis (BioDaq, Reseach Diet Inc);
- Radiotelemetry system for wireless acquisition of heart rate, blood pressure and body temperature (Data Science International, Saint Paul MN);
- Activity systems:
- Infrared-based home-cage locomotor activity (The Actimeter, Technosmart, Rome, Italy)
- Running Wheels (La Fayette, IN);
- Glucose and Insulin Tolerance test
- State-of-the-art surgery suite (for rats and mice).
- Mouse model of chronic psychosocial stress and a selection of behavioral tests for anxiety/depression.
- We also offer support and consultation for data analysis and interpretation.
These spaces meet the expectations of the Institutional Animal Care and Use Committee (IACUC) requirements and is inspected twice yearly by the IACUC and once a month by Research Animal Resources (RAR).
Department of Integrative Biology and Physiology
Integrative Biology and Physiology (IBP) is dedicated to an integrative systems biology approach to bio-medical discovery. We partner with colleagues across disciplines to investigate questions ranging from gene/molecule to the intact animal, while striving for excellence in research and dissemination of new knowledge with local, national, and global impact. It is our goal to discover new technologies by expanding our knowledge base and discovering new ways to integrate the biological disciplines including cardiovascular disease, obesity, stress and metabolic disorders on whole animal levels.