Bioprinting facility

The University of Minnesota’s Bioprinting Facility studies human cell viability, proliferation, migration, and differentiation, as well as tissue morphogenesis, in three-dimensionally printed tissue constructs.  We synthesize synthetic and natural biomaterials for use as “inks” in bioprinting projects. We employ a variety of bioprinting techniques and hydrogel crosslinking methods.

The facility provides bioprinters, reagents, consumables, an automatic imaging system, and personalized training sessions to meet all of your bioprinting research needs.

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Available Equipment

Inkredible+ Bioprinter

Inkredible+ Bioprinter

Inkredible+ Printer
The Inkredible+ is a pneumatic-based extrusion system with dual print heads and built-in UV LED curing that allows for quick and easy bioprinting of living tissues.

BIO X Bioprinter

BIO X Bioprinter

Bio X Printer
A user-friendly and flexible bioprinter with interchangeable printheads, allowing compatibility with virtually any material to offer a wide range of applications. 

BIONOVAX

BIONOVAX

BioNovaX: Digital Light Processing Bioprinter

The BionovaX uses Digital Light Processing (DLP) to enable high-resolution live cell printing.

R-GEN 200 Bioprinting Station

R-GEN 200 Bioprinting Station

RegenHU R-GEN 200 Bioprinting Station

Combine jetting, contact dispensing and electrowriting technologies with a full range of auxiliary process options to build simple or complex cell-laden constructs.

Ultimaker 2 Extended+ 3D Printer

Ultimaker 2 Extended+ 3D Printer

Ultimaker 2+ Extended
Thermoplastic 3D printer with the ability to create custom parts to assist in 3D bioprinting. 

Invitrogen EVOS FL Auto 2 Cell Imaging System

Invitrogen EVOS FL Auto 2 Cell Imaging System

evos
Fully automated imaging system designed with advanced capabilities to simplify demanding cell-based imaging applications such as live-cell imaging, image tiling, and Z-stacking.

Mach-1 Micromechanical Tissue Testing System

Mach-1 Micromechanical Tissue Testing System

mach 1

A unique system with customizable features to determine the mechanical properties of biomaterials, tissues, and soft materials in various applications. 

Desktops for CAD Design and Bioprinting File Preparation

Desktops for CAD Design and Bioprinting File Preparation

comps

Coming Soon: Laser-Assisted Bioprinter for Laser-Induced Forward Transfers

Coming Soon: Laser-Assisted Bioprinter for Laser-Induced Forward Transfers

laser-assisted bioprinter

 


 

Faculty

Facility Director

Facility Manager

Facility Manager

Kyleigh Pacello

Headshot of facility manager

 

 


 

Available Consumables and Reagents

Bioprinting Consumables

Bioprinting Consumables

consumables
We have syringe barrels, caps, pistons, and nozzle tips of varying gauges and lengths available to purchase. 

Sterile Consumables

Sterile Consumables

sterile

 

Bioprinting supplies can be provided sterile to mitigate contamination of cell-laden 3D printed constructs. 

Pluronic F-127

Pluronic F-127

pluronic
Pluronic is great sacrificial material due to its reverse gelation. It is a gel at room temperature and liquifies at colder temperatures. 

Gelatin Methacryloyl (GelMA)

Gelatin Methacryloyl (GelMA)

gelma
GelMA is produced through the modification of gelatin with methacrylic anhydride. The amino groups on gelatin's side chains are replaced with methacryloyl groups. The final product is able to crosslink in the presence of a photoinitiator (LAP) and UV light. 

Gelatin from Porcine Skin, 300 Gram Bloom Strength

Gelatin from Porcine Skin, 300 Gram Bloom Strength

gelatin

Sodium Alginate

Sodium Alginate

alginate
This substance is a natural polymer derived from algae and is capable of ionic crosslinking in the presence of divalent cations. The most common crosslinking method is submerging in a bath of CaClsolution.

Custom Support Parts

Custom Support Parts

custom
Custom ABS, ASA, Polypropylene, Nylon, and Polycaprolactone parts made by the Ultimaker 3D printer.

 


 

Dual Extrusion

Inkredible+ Bioprinter Loaded with Two Different Materials

Inkredible+ Bioprinter Loaded with Two Different Materials

dual

Dual Extrusion Mid-Print

Dual Extrusion Mid-Print

midprint

Human Nose Model with Two Materials

Human Nose Model with Two Materials

nose

Human Nose Model with Two Materials

Human Nose Model with Two Materials

nose

Human Nose Model with Two Materials

Human Nose Model with Two Materials

nose

 


 

Videos and Media Coverage

 

University of Minnesota Medical Bulletin -- Made To Order

 

 

 

 

Contact Information

 

Point of Contact

Kyleigh Pacello
Facility Manager


Lab location

Nils Hasselmo Hall
Room 1-279


Mailing address

312 Church St SE
NHH, Room 1-279
Minneapolis, MN 55455